{"id":6352,"date":"2025-12-15T09:28:16","date_gmt":"2025-12-15T09:28:16","guid":{"rendered":"https:\/\/www.green-ivf.de\/?p=6352"},"modified":"2025-12-15T14:53:41","modified_gmt":"2025-12-15T14:53:41","slug":"hla-c-ve-kir-doellenme-icin-ne-anlama-gelir","status":"publish","type":"post","link":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/","title":{"rendered":"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"6352\" class=\"elementor elementor-6352 elementor-6349\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36419767 e-flex e-con-boxed e-con e-parent\" data-id=\"36419767\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d5ac397 elementor-widget elementor-widget-post-info\" data-id=\"d5ac397\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-32f8e33 elementor-inline-item\" itemprop=\"author\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-user-circle\" viewBox=\"0 0 496 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M248 104c-53 0-96 43-96 96s43 96 96 96 96-43 96-96-43-96-96-96zm0 144c-26.5 0-48-21.5-48-48s21.5-48 48-48 48 21.5 48 48-21.5 48-48 48zm0-240C111 8 0 119 0 256s111 248 248 248 248-111 248-248S385 8 248 8zm0 448c-49.7 0-95.1-18.3-130.1-48.4 14.9-23 40.4-38.6 69.6-39.5 20.8 6.4 40.6 9.6 60.5 9.6s39.7-3.1 60.5-9.6c29.2 1 54.7 16.5 69.6 39.5-35 30.1-80.4 48.4-130.1 48.4zm162.7-84.1c-24.4-31.4-62.1-51.9-105.1-51.9-10.2 0-26 9.6-57.6 9.6-31.5 0-47.4-9.6-57.6-9.6-42.9 0-80.6 20.5-105.1 51.9C61.9 339.2 48 299.2 48 256c0-110.3 89.7-200 200-200s200 89.7 200 200c0 43.2-13.9 83.2-37.3 115.9z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-author\">\n\t\t\t\t\t\t\t<span class=\"elementor-post-info__item-prefix\">von <\/span>\n\t\t\t\t\t\t\t\t\t\tProf. Christian Gnoth\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d21ca8f elementor-widget elementor-widget-text-editor\" data-id=\"4d21ca8f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>HLA-C ve KIR asl\u0131nda nedir?<\/strong><\/h3><p>Bir gebeli\u011fin olu\u015fabilmesi i\u00e7in, yar\u0131 yabanc\u0131 embriyonun (genetik ve imm\u00fcnolojik olarak yar\u0131 baba yar\u0131 anne) rahme yerle\u015fmesi gerekir. Bu s\u00fcre\u00e7 sadece hormonlar taraf\u0131ndan de\u011fil, ayn\u0131 zamanda annenin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi taraf\u0131ndan da kontrol edilir.<br>Bu s\u00fcre\u00e7te iki \u00f6nemli fakt\u00f6r rol oynar: <\/p><ul><li><strong>HLA-C:<\/strong> Embriyo h\u00fccrelerinde bulunan ve anne ile babadan kal\u0131t\u0131lan bir \u00f6zelliktir. \u00d6nemli: Ebeveynler ayn\u0131 kalsa bile, her embriyonun kendine \u00f6zg\u00fc kombinasyonlar\u0131 vard\u0131r. <\/li><li><strong>KIR-Resept\u00f6rleri:<\/strong> Rahim zar\u0131ndaki belirli savunma h\u00fccrelerinde (uNK h\u00fccreleri = &#8220;uterin do\u011fal \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccreler&#8221; olarak adland\u0131r\u0131l\u0131r) bulunan tan\u0131ma \u00f6zellikleridir. Bunlar embriyonun &#8220;korumalar\u0131d\u0131r&#8221;. <\/li><\/ul><p>Embriyonun HLA-C imzas\u0131 ve annenin KIR durumu e\u015fle\u015fti\u011finde, embriyo daha iyi yerle\u015febilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3b4cf94 elementor-widget elementor-widget-text-editor\" data-id=\"3b4cf94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Ayn\u0131 ebeveynlerin embriyolar\u0131 neden farkl\u0131d\u0131r?<\/strong><\/h3><p>Anne ve baba ayn\u0131 kalsa bile, her \u00e7ocuk genlerinin farkl\u0131 bir kar\u0131\u015f\u0131m\u0131n\u0131 miras al\u0131r. Bu \u015fu anlama gelir: <\/p><ul><li>Bir embriyo, HLA-C ve maternal KIR&#8217;in uyumlu bir kombinasyonuna sahip olabilir.<\/li><li>Bir sonraki embriyo daha az uygun bir kombinasyona sahip olabilir.<\/li><\/ul><p>Bir siklusta gebelik olu\u015fmazsa, bunun nedeni \u00e7o\u011funlukla genetik fakt\u00f6rlerdir (mayoz ve mitoz hatalar\u0131). Ancak yukar\u0131da bahsedilen imm\u00fcnolojik nedenlerden dolay\u0131 baz\u0131 sikluslar\u0131n (t\u00fcp bebekte bile) gebeli\u011fe yol a\u00e7mamas\u0131 da m\u00fcmk\u00fcnd\u00fcr. Bunun nedeni, <strong>&#8220;temelde bir sorun olmas\u0131&#8221; de\u011fil,<\/strong> her embriyoda farkl\u0131 olan <strong>genlerin rastgele kombinasyonudur<\/strong>.  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d74c682 elementor-widget elementor-widget-text-editor\" data-id=\"d74c682\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>Hangi kombinasyonlar daha az uygun kabul edilir?<\/strong><\/h3><p>Nadir durumlarda, yerle\u015fmenin <strong>daha g\u00fc\u00e7l\u00fc bir \u015fekilde yava\u015flamas\u0131<\/strong> meydana gelir.<br>Bu durum \u00f6zellikle, babadan belirli bir HLA-C tipi (&#8220;C1&#8221;, her zaman de\u011fil, embriyodan embriyoya farkl\u0131l\u0131k g\u00f6sterir) miras alan embriyolar\u0131 ta\u015f\u0131yan, aktive edici \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccre resept\u00f6rleri olmayan (genetik olarak belirlendi\u011fi i\u00e7in her zaman b\u00f6yledir) belirli bir KIR tipine (&#8220;KIR-AA&#8221;) sahip kad\u0131nlar\u0131 etkiler. Bu kombinasyon, rahim zar\u0131n\u0131n yerle\u015fmeyi engellemesine veya zorla\u015ft\u0131rmas\u0131na ve ard\u0131ndan plasenta geli\u015fimini \u00e7ok fazla engellemesine neden olabilir, bu da gebelikte d\u00fc\u015f\u00fcklere veya gebelik komplikasyonlar\u0131na (gestozlar olarak adland\u0131r\u0131l\u0131r) yol a\u00e7abilir. <\/p><p>\u00d6nemli, bu kombinasyon bir gebelik i\u00e7in <strong>mutlak bir d\u0131\u015flama de\u011fildir<\/strong> &#8211; bu kombinasyona sahip bir\u00e7ok kad\u0131n tamamen sorunsuz bir \u015fekilde hamile kal\u0131r, \u00e7\u00fcnk\u00fc bir embriyonun ne kadar iyi yerle\u015fti\u011fi konusunda bir\u00e7ok ba\u015fka fakt\u00f6r rol oynar (embriyo canl\u0131l\u0131\u011f\u0131).<\/p><p>KIR genlerinin belirlenmesi a\u015fa\u011f\u0131daki durumlarda anlaml\u0131 olabilir:<\/p><ul><li>tekrarlayan erken d\u00fc\u015f\u00fckler<\/li><li>iyi embriyolara ra\u011fmen yerle\u015fme olmamas\u0131 (IVF\/ICSI)<\/li><li>\u00f6nceki gebeliklerde plasentasyon sorunlar\u0131na dair belirtiler<\/li><\/ul><p>KIR tiplemesi (kan testi), HLA-C tiplemesinden daha \u00f6nemlidir.<\/p><p>Yukar\u0131da belirtilen durumlarda, imm\u00fcnolojik yap\u0131lar\u0131 anlamak, olas\u0131 nedenleri daraltmaya ve daha sonraki tedaviyi buna g\u00f6re uyarlamaya yard\u0131mc\u0131 olur, \u00f6rne\u011fin yetersiz aktivasyon durumunda \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccreler taraf\u0131ndan yetersiz \u00fcretilen b\u00fcy\u00fcme fakt\u00f6rleri i\u00e7eren \u00f6zel ila\u00e7lar\u0131n verilmesi (G-CSF). Tedavi ayr\u0131ca a\u015fa\u011f\u0131daki yollarla da optimize edilebilir: <\/p><ul><li>siklusun uyarlanm\u0131\u015f hormonal deste\u011fi, burada \u00f6zellikle progesteron \u00f6nemlidir, \u00e7\u00fcnk\u00fc bu uterin \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccrelerin do\u011fal bir aktivat\u00f6r\u00fcd\u00fcr<\/li><li>se\u00e7ilmi\u015f vakalarda anti-enflamatuar veya imm\u00fcnomod\u00fclat\u00f6r tedaviler<\/li><li>bir IVF&#8217;de embriyo transferi i\u00e7in uygun embriyonun do\u011fru se\u00e7imi<\/li><li>erken gebeli\u011fin yak\u0131ndan izlenmesi<\/li><\/ul><p>\u00d6nemli olan, ba\u011f\u0131\u015f\u0131kl\u0131k sistemini bask\u0131lamak de\u011fil, dengesini yeniden kurmakt\u0131r.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fc77385 e-con-full e-flex e-con e-child\" data-id=\"fc77385\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2d69d8e ha-has-bg-overlay elementor-widget elementor-widget-image\" data-id=\"2d69d8e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"741\" height=\"723\" src=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium-en-2.jpg\" class=\"attachment-full size-full wp-image-6368\" alt=\"\" srcset=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium-en-2.jpg 741w, https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium-en-2-300x293.jpg 300w\" sizes=\"(max-width: 741px) 100vw, 741px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">\u015eekil: Vital embriyo, olumsuz ko\u015fullarda bile (defansif endometrium) iyi yerle\u015fme \u015fans\u0131na sahiptir. S\u0131n\u0131rl\u0131 vitaliteye sahip embriyonun ba\u015far\u0131l\u0131 bir gebelik i\u00e7in en iyi yerle\u015fme ko\u015fullar\u0131na (reseptif endometrium) ihtiyac\u0131 vard\u0131r. \u0130nsanlarda embriyolar\u0131n \u00e7o\u011funun s\u0131n\u0131rl\u0131 bir canl\u0131l\u0131\u011fa sahip olmas\u0131 normaldir.<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>HLA-C ve KIR, embriyo ile rahim aras\u0131ndaki imm\u00fcnolojik ileti\u015fimi y\u00f6netir. Bunlar\u0131n kombinasyonu yerle\u015fmeyi, plasenta geli\u015fimini ve dolay\u0131s\u0131yla stabil bir gebelik \u015fans\u0131n\u0131 etkiler. <\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"iawp_total_views":4,"footnotes":""},"categories":[244,119,137],"tags":[250,245,249,251,246,252,247,248],"class_list":["post-6352","post","type-post","status-publish","format-standard","hentry","category-arastirma","category-haberler","category-yayin","tag-embriyo-canliligi","tag-hla-c","tag-immuenolojik-denge","tag-kir-aa-tipi","tag-kir-reseptoerleri","tag-plasentasyon-gestozlar","tag-uterin-oeldueruecue-huecreler-unk-huecreleri","tag-yerlesme-implantasyon"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir? | green-ivf | Kinderwunsch-Zentrum in NRW<\/title>\n<meta name=\"description\" content=\"HLA-C ve KIR, embriyonun imm\u00fcnolojik olarak yerle\u015fmesini etkiler ve gebelik ile plasenta i\u00e7in \u00f6nemli bir rol oynar.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir? | green-ivf | Kinderwunsch-Zentrum in NRW\" \/>\n<meta property=\"og:description\" content=\"HLA-C ve KIR, embriyonun imm\u00fcnolojik olarak yerle\u015fmesini etkiler ve gebelik ile plasenta i\u00e7in \u00f6nemli bir rol oynar.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/\" \/>\n<meta property=\"og:site_name\" content=\"green-ivf | Kinderwunsch-Zentrum in NRW\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-15T09:28:16+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-15T14:53:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"741\" \/>\n\t<meta property=\"og:image:height\" content=\"723\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Prof. Christian Gnoth\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"Prof. Christian Gnoth\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/\"},\"author\":{\"name\":\"Prof. Christian Gnoth\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#\\\/schema\\\/person\\\/66c8d3c2664ed3dbf9ccde8a8b7609ca\"},\"headline\":\"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir?\",\"datePublished\":\"2025-12-15T09:28:16+00:00\",\"dateModified\":\"2025-12-15T14:53:41+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/\"},\"wordCount\":637,\"publisher\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.green-ivf.de\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/HLA-C-KIR-transformiertes-Endometrium.jpg\",\"keywords\":[\"Embriyo canl\u0131l\u0131\u011f\u0131\",\"HLA-C\",\"imm\u00fcnolojik denge\",\"KIR-AA-Tipi\",\"KIR-Resept\u00f6rleri\",\"Plasentasyon \\\/ Gestozlar\",\"uterin \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccreler (uNK h\u00fccreleri)\",\"Yerle\u015fme (\u0130mplantasyon)\"],\"articleSection\":[\"Ara\u015ft\u0131rma\",\"haberler\",\"Yay\u0131n\"],\"inLanguage\":\"tr\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/\",\"url\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/\",\"name\":\"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir? | green-ivf | Kinderwunsch-Zentrum in NRW\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.green-ivf.de\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/HLA-C-KIR-transformiertes-Endometrium.jpg\",\"datePublished\":\"2025-12-15T09:28:16+00:00\",\"dateModified\":\"2025-12-15T14:53:41+00:00\",\"description\":\"HLA-C ve KIR, embriyonun imm\u00fcnolojik olarak yerle\u015fmesini etkiler ve gebelik ile plasenta i\u00e7in \u00f6nemli bir rol oynar.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.green-ivf.de\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/HLA-C-KIR-transformiertes-Endometrium.jpg\",\"contentUrl\":\"https:\\\/\\\/www.green-ivf.de\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/HLA-C-KIR-transformiertes-Endometrium.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/ana-sayfa\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#website\",\"url\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/\",\"name\":\"green-ivf | Kinderwunsch-Zentrum in NRW\",\"description\":\"Praxisklinik f\u00fcr Reproduktionsmedizin und Endokrinologie |\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#organization\"},\"alternateName\":\"Kinderwunschzentrum in NRW\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"tr\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#organization\",\"name\":\"Greevenbroicher Endokrinologie- & IVF-Zentrum\",\"alternateName\":\"green-ivf: Praxisklinik f\u00fcr Reproduktionsmedizin und Endokrinologie (BAG)\",\"url\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.green-ivf.de\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/cropped-Green-ivf-Grevenbroicher-Endokrinologie-ivf-Zentrum-fav.png\",\"contentUrl\":\"https:\\\/\\\/www.green-ivf.de\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/cropped-Green-ivf-Grevenbroicher-Endokrinologie-ivf-Zentrum-fav.png\",\"width\":512,\"height\":512,\"caption\":\"Greevenbroicher Endokrinologie- & IVF-Zentrum\"},\"image\":{\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.green-ivf.de\\\/tr\\\/#\\\/schema\\\/person\\\/66c8d3c2664ed3dbf9ccde8a8b7609ca\",\"name\":\"Prof. Christian Gnoth\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/0e5706e4c93ba3617e251253fadda0bd2b7a3a7cf9a58dac79809276777e0eb0?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/0e5706e4c93ba3617e251253fadda0bd2b7a3a7cf9a58dac79809276777e0eb0?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/0e5706e4c93ba3617e251253fadda0bd2b7a3a7cf9a58dac79809276777e0eb0?s=96&d=mm&r=g\",\"caption\":\"Prof. Christian Gnoth\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir? | green-ivf | Kinderwunsch-Zentrum in NRW","description":"HLA-C ve KIR, embriyonun imm\u00fcnolojik olarak yerle\u015fmesini etkiler ve gebelik ile plasenta i\u00e7in \u00f6nemli bir rol oynar.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/","og_locale":"tr_TR","og_type":"article","og_title":"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir? | green-ivf | Kinderwunsch-Zentrum in NRW","og_description":"HLA-C ve KIR, embriyonun imm\u00fcnolojik olarak yerle\u015fmesini etkiler ve gebelik ile plasenta i\u00e7in \u00f6nemli bir rol oynar.","og_url":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/","og_site_name":"green-ivf | Kinderwunsch-Zentrum in NRW","article_published_time":"2025-12-15T09:28:16+00:00","article_modified_time":"2025-12-15T14:53:41+00:00","og_image":[{"width":741,"height":723,"url":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium.jpg","type":"image\/jpeg"}],"author":"Prof. Christian Gnoth","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"Prof. Christian Gnoth","Tahmini okuma s\u00fcresi":"3 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#article","isPartOf":{"@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/"},"author":{"name":"Prof. Christian Gnoth","@id":"https:\/\/www.green-ivf.de\/tr\/#\/schema\/person\/66c8d3c2664ed3dbf9ccde8a8b7609ca"},"headline":"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir?","datePublished":"2025-12-15T09:28:16+00:00","dateModified":"2025-12-15T14:53:41+00:00","mainEntityOfPage":{"@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/"},"wordCount":637,"publisher":{"@id":"https:\/\/www.green-ivf.de\/tr\/#organization"},"image":{"@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#primaryimage"},"thumbnailUrl":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium.jpg","keywords":["Embriyo canl\u0131l\u0131\u011f\u0131","HLA-C","imm\u00fcnolojik denge","KIR-AA-Tipi","KIR-Resept\u00f6rleri","Plasentasyon \/ Gestozlar","uterin \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccreler (uNK h\u00fccreleri)","Yerle\u015fme (\u0130mplantasyon)"],"articleSection":["Ara\u015ft\u0131rma","haberler","Yay\u0131n"],"inLanguage":"tr"},{"@type":"WebPage","@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/","url":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/","name":"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir? | green-ivf | Kinderwunsch-Zentrum in NRW","isPartOf":{"@id":"https:\/\/www.green-ivf.de\/tr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#primaryimage"},"image":{"@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#primaryimage"},"thumbnailUrl":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium.jpg","datePublished":"2025-12-15T09:28:16+00:00","dateModified":"2025-12-15T14:53:41+00:00","description":"HLA-C ve KIR, embriyonun imm\u00fcnolojik olarak yerle\u015fmesini etkiler ve gebelik ile plasenta i\u00e7in \u00f6nemli bir rol oynar.","breadcrumb":{"@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/"]}]},{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#primaryimage","url":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium.jpg","contentUrl":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/12\/HLA-C-KIR-transformiertes-Endometrium.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.green-ivf.de\/tr\/hla-c-ve-kir-doellenme-icin-ne-anlama-gelir\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/www.green-ivf.de\/tr\/ana-sayfa\/"},{"@type":"ListItem","position":2,"name":"HLA-C ve KIR d\u00f6llenme i\u00e7in ne anlama gelir?"}]},{"@type":"WebSite","@id":"https:\/\/www.green-ivf.de\/tr\/#website","url":"https:\/\/www.green-ivf.de\/tr\/","name":"green-ivf | Kinderwunsch-Zentrum in NRW","description":"Praxisklinik f\u00fcr Reproduktionsmedizin und Endokrinologie |","publisher":{"@id":"https:\/\/www.green-ivf.de\/tr\/#organization"},"alternateName":"Kinderwunschzentrum in NRW","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.green-ivf.de\/tr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"tr"},{"@type":"Organization","@id":"https:\/\/www.green-ivf.de\/tr\/#organization","name":"Greevenbroicher Endokrinologie- & IVF-Zentrum","alternateName":"green-ivf: Praxisklinik f\u00fcr Reproduktionsmedizin und Endokrinologie (BAG)","url":"https:\/\/www.green-ivf.de\/tr\/","logo":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/www.green-ivf.de\/tr\/#\/schema\/logo\/image\/","url":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2024\/11\/cropped-Green-ivf-Grevenbroicher-Endokrinologie-ivf-Zentrum-fav.png","contentUrl":"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2024\/11\/cropped-Green-ivf-Grevenbroicher-Endokrinologie-ivf-Zentrum-fav.png","width":512,"height":512,"caption":"Greevenbroicher Endokrinologie- & IVF-Zentrum"},"image":{"@id":"https:\/\/www.green-ivf.de\/tr\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.green-ivf.de\/tr\/#\/schema\/person\/66c8d3c2664ed3dbf9ccde8a8b7609ca","name":"Prof. Christian Gnoth","image":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/secure.gravatar.com\/avatar\/0e5706e4c93ba3617e251253fadda0bd2b7a3a7cf9a58dac79809276777e0eb0?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/0e5706e4c93ba3617e251253fadda0bd2b7a3a7cf9a58dac79809276777e0eb0?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/0e5706e4c93ba3617e251253fadda0bd2b7a3a7cf9a58dac79809276777e0eb0?s=96&d=mm&r=g","caption":"Prof. Christian Gnoth"}}]}},"_links":{"self":[{"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/posts\/6352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/comments?post=6352"}],"version-history":[{"count":0,"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/posts\/6352\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/media?parent=6352"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/categories?post=6352"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.green-ivf.de\/tr\/wp-json\/wp\/v2\/tags?post=6352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}