{"id":5430,"date":"2024-11-10T13:41:56","date_gmt":"2024-11-10T13:41:56","guid":{"rendered":"https:\/\/www.green-ivf.de\/ire-test-immunohistochemical-receptivity-test-of-the-endometrium\/"},"modified":"2025-09-13T15:47:45","modified_gmt":"2025-09-13T15:47:45","slug":"ire-test-immunohistochemical-receptivity-test-of-the-endometrium","status":"publish","type":"page","link":"https:\/\/www.green-ivf.de\/en\/desire-to-have-children\/ire-test-immunohistochemical-receptivity-test-of-the-endometrium\/","title":{"rendered":"IRE Test &#8211; Immunohistochemical Receptivity Test of the Endometrium"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5430\" class=\"elementor elementor-5430 elementor-29\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b33bb6e e-flex e-con-boxed e-con e-parent\" data-id=\"7b33bb6e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;shape_divider_bottom&quot;:&quot;multi-wave&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-shape elementor-shape-bottom\" aria-hidden=\"true\" data-negative=\"false\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 4080 400\" preserveAspectRatio=\"none\">\n<path class=\"elementor-shape-fill ha-shape-divider\" opacity=\"0.2\" enable-background=\"new    \" d=\"M4080,79.3V0L1179.4,0v79.3c0,0,694.9,437.4,1471.3,275.6\n\tS3575.7-152.5,4080,79.3z\"\/>\n<path class=\"elementor-shape-fill ha-shape-divider\" opacity=\"0.2\" enable-background=\"new    \" d=\"M2249,79.3V0L0,0l0,79.3c0,0,43.3,437.4,819.8,275.6S1744.7-152.5,2249,79.3z\"\/>\n<path class=\"elementor-shape-fill ha-shape-divider\" opacity=\"0.2\" enable-background=\"new    \" d=\"M2631.6,49.8c0,0-596.3,547.3-1468.8,230.2S0,95.6,0,95.6L0,0l2631.6,0V49.8z\"\/>\n<path class=\"elementor-shape-fill ha-shape-divider\" opacity=\"0.2\" enable-background=\"new    \" d=\"M4080,95.6c0,0-428.4,501.5-1208.9,184.4S1831,95.6,1831,95.6V0l2249,0V95.6z\"\/>\n<path class=\"elementor-shape-fill ha-shape-divider\" d=\"M4080,0v192.6c-392.4,177-703.2,95.6-1075-34.1c-214.6-74.8-508-126-839.1,6.1c-149.2,59.5-447.2,203.4-1026.2,10.8\n\tC313.2-99.5,0,95.6,0,95.6L0,0l2249,0L4080,0z\"\/>\n<\/svg>\n\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-64cbe7b e-con-full e-flex e-con e-child\" data-id=\"64cbe7b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c4005b6 elementor-widget elementor-widget-heading\" data-id=\"c4005b6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">IRE Test<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4b06f6c6 e-con-full e-flex e-con e-parent\" data-id=\"4b06f6c6\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-59cd8e25 elementor-align-right elementor-mobile-align-left elementor-widget elementor-widget-breadcrumbs\" data-id=\"59cd8e25\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"breadcrumbs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p id=\"breadcrumbs\"><span><span><a href=\"https:\/\/www.green-ivf.de\/en\/homepage\/\">Startseite<\/a><\/span><\/span><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d1a1c12 e-flex e-con-boxed e-con e-parent\" data-id=\"d1a1c12\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-48fc0879 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"48fc0879\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#Implantationsdiagnostik\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"hm hm-arrow-right1\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Implantation diagnostics<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#ire\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"hm hm-arrow-right1\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Immunohistochemical receptivity test of the endometrium (IRE)<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#erweitertescreening\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"hm hm-arrow-right1\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Extended screening in addition to the IRE test<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#patienteninformationen\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"hm hm-arrow-right1\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Patient information<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-481e367d e-flex e-con-boxed e-con e-parent\" data-id=\"481e367d\" data-element_type=\"container\" data-e-type=\"container\" id=\"wechseljahre\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-73020f5a e-con-full e-flex e-con e-child\" data-id=\"73020f5a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t<div class=\"elementor-element elementor-element-4ab1978a e-con-full e-flex e-con e-child\" data-id=\"4ab1978a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-03e3415 uael-heading-align-left elementor-widget elementor-widget-uael-advanced-heading\" data-id=\"03e3415\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"uael-advanced-heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"uael-module-content uael-heading-wrapper\">\n\t\t\t\t\t\t\t\t\t\t<div class=\"uael-sub-heading elementor-inline-editing\" data-elementor-setting-key=\"sub_heading\" data-elementor-inline-editing-toolbar=\"advanced\" >When the desire to have children remains unfulfilled <\/div>\n\t\t\t\n\t\t\t<h2 class=\"uael-heading\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"uael-heading-text elementor-inline-editing uael-size--default\" data-elementor-setting-key=\"heading_title\" data-elementor-inline-editing-toolbar=\"basic\">Identify causes and treat them in a targeted manner<\/span>\n\t\t\t\t\t\t\t<\/h2>\n\n\t\t\t\n\t\t\t\t\t\t<div class=\"uael-module-content uael-separator-parent\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-separator\"><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2286f08 elementor-widget elementor-widget-text-editor\" data-id=\"2286f08\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Sometimes, fertility treatment remains unsuccessful despite optimal conditions, or a pregnancy does not develop properly and results in a miscarriage.<\/p><p>The causes of this can lie in the embryo itself or, among other things, in the uterine lining (endometrium), the place where the embryo is supposed to implant and develop undisturbed, protected from the maternal immune system.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2521ff6 e-con-full e-flex e-con e-child\" data-id=\"2521ff6\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-17f8f6bc elementor-widget elementor-widget-image\" data-id=\"17f8f6bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1000\" height=\"740\" src=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/04\/BP5I1450-02.jpg\" class=\"attachment-full size-full wp-image-4920\" alt=\"Dr. med. Nina Bachmann during a sonography with a patient\" srcset=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/04\/BP5I1450-02.jpg 1000w, https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/04\/BP5I1450-02-300x222.jpg 300w, https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/04\/BP5I1450-02-768x568.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2a57f7b5 e-flex e-con-boxed e-con e-parent\" data-id=\"2a57f7b5\" data-element_type=\"container\" data-e-type=\"container\" id=\"Implantationsdiagnostik\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-328f437d e-con-full e-flex e-con e-child\" data-id=\"328f437d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t<div class=\"elementor-element elementor-element-31d9b23a e-con-full e-flex e-con e-child\" data-id=\"31d9b23a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ce4976f uael-heading-align-left elementor-widget elementor-widget-uael-advanced-heading\" data-id=\"ce4976f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"uael-advanced-heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"uael-module-content uael-heading-wrapper\">\n\t\t\t\t\t\t\t\t\t\t<div class=\"uael-sub-heading elementor-inline-editing\" data-elementor-setting-key=\"sub_heading\" data-elementor-inline-editing-toolbar=\"advanced\" >Implantation diagnostics<\/div>\n\t\t\t\n\t\t\t<h2 class=\"uael-heading\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"uael-heading-text elementor-inline-editing uael-size--default\" data-elementor-setting-key=\"heading_title\" data-elementor-inline-editing-toolbar=\"basic\">Identify and treat implantation disorders<\/span>\n\t\t\t\t\t\t\t<\/h2>\n\n\t\t\t\n\t\t\t\t\t\t<div class=\"uael-module-content uael-separator-parent\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-separator\"><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54ee3022 elementor-widget elementor-widget-text-editor\" data-id=\"54ee3022\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The uterine lining is immunologically highly specialized to selectively allow the foreign embryo to implant (receptive), but to ward off bacteria, for example (defensive). Sometimes this does not work optimally and implantation disorders occur. The vital embryo implants in the receptive endometrium with a high chance of an ongoing pregnancy.  <\/p><p>Implantation disorders can occur in the defensive endometrium, which in particularly severe cases can lead to a miscarriage. The limited vital embryo does not implant under defensive conditions in the endometrium. <\/p><p>In the highly receptive endometrium, endometrial selection is less effective, implantation takes place but an abortion can be the result. But normal, ongoing pregnancies are also possible: every embryo, even the &#8220;bad&#8221; one, has its chance (see Fig. Embryo-maternal dialogue). <\/p><p>We and our selected partners from pathology and laboratory medicine have been intensively involved with these connections for a long time. According to our experience and the scientific literature, further investigations are recommended if an implantation disorder is suspected, in particular killer cell receptor typing and the immunohistochemical receptivity test of the endometrium, in order to increase the chances of less vital embryos through suitable measures. <\/p><p>To protect the uterine lining, we always try to avoid a curettage in the event of an early miscarriage and therefore prefer to perform a medical termination of pregnancy on an outpatient basis with mifepristone and misoprostol under ultrasound and hormone monitoring.<\/p><p>We are happy to offer our expertise on these and other helpful examinations and finally the discussion of the results and therapeutic options.<\/p><p>The therapeutic spectrum includes, among other things, the administration of a suitable antibiotic, the low-dose administration of cortisone, aspirin, heparin and finally the administration of the growth factor G-CSF. Often the measures are combined with an optimization of the vaginal and endometrial microbiome (including lactobacilli). <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-56a7b04e e-flex e-con-boxed e-con e-parent\" data-id=\"56a7b04e\" data-element_type=\"container\" data-e-type=\"container\" id=\"ire\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7451f875 e-con-full e-flex e-con e-child\" data-id=\"7451f875\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t<div class=\"elementor-element elementor-element-33066199 e-con-full e-flex e-con e-child\" data-id=\"33066199\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6265b783 uael-heading-align-left elementor-widget elementor-widget-uael-advanced-heading\" data-id=\"6265b783\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"uael-advanced-heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"uael-module-content uael-heading-wrapper\">\n\t\t\t\t\t\t\t\t\t\t<div class=\"uael-sub-heading elementor-inline-editing\" data-elementor-setting-key=\"sub_heading\" data-elementor-inline-editing-toolbar=\"advanced\" >Extended diagnostics - IRE Test<\/div>\n\t\t\t\n\t\t\t<h2 class=\"uael-heading\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"uael-heading-text elementor-inline-editing uael-size--default\" data-elementor-setting-key=\"heading_title\" data-elementor-inline-editing-toolbar=\"basic\">Analysis of the uterine lining for the diagnosis of implantation disorders<\/span>\n\t\t\t\t\t\t\t<\/h2>\n\n\t\t\t\n\t\t\t\t\t\t<div class=\"uael-module-content uael-separator-parent\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-separator\"><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7fdbcd4a elementor-widget elementor-widget-text-editor\" data-id=\"7fdbcd4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Extended diagnostics for unfulfilled desire to have children, especially after repeated miscarriages or unsuccessful IVF therapy cycles, includes examination of the uterine lining as an important immunological organ.<\/p><p>For this purpose, the uterine lining is first built up with estradiol and later transformed with a progestogen in order to be able to take a tissue sample from the uterine lining in a hormone-phase-appropriate and precisely datable manner (to the optimum of a presumed implantation). A thin catheter is used to remove an amount of mucous membrane about the size of a lentil to a maximum of a pea from the uterine cavity as part of a gynecological examination and examined using fine tissue analysis. <\/p><p>The fine tissue examination results are compared with ultrasound findings and blood results and it is checked whether the architecture and fine tissue remodeling of the uterine lining has taken place in accordance with the cycle phase. Particular attention is paid to the colonization with different immune cells, because about every 3rd cell in the uterine lining in the 2nd half of the cycle is an immune cell; if necessary, it is also examined whether the uterine lining cells divide accordingly (mitosis index) and also form hormone receptors (estrogen and progesterone receptors) in accordance with the cycle phase.  <\/p><p>From these results, important conclusions can be drawn about the receptivity (readiness for conception) of the uterine lining and, if necessary, corresponding therapies can be indicated in connection with further examinations (KIR typing, autoimmune screening, coagulation diagnostics, chromosome analysis).<\/p><p>Occasionally, this uterine lining removal is performed together with an ultrasound contrast agent examination to visualize the uterus, ovaries and fallopian tubes with verification of patency. The removal of the uterine lining sample for the purpose of immunohistochemical examination in the programmed cycle is not a service of the statutory health insurance. <\/p><p>The fine tissue examinations are also only partially covered by the statutory health insurance companies. For patients with statutory health insurance, a co-payment of approx. \u20ac150-300 may be incurred. For privately insured patients, the insurance usually, but not always, covers all services.  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ba2af4a elementor-align-left elementor-widget elementor-widget-button\" data-id=\"ba2af4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation_tablet&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md\" href=\"https:\/\/www.green-ivf.de\/kontakt\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Make an appointment<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c18820d e-flex e-con-boxed e-con e-parent\" data-id=\"c18820d\" data-element_type=\"container\" data-e-type=\"container\" id=\"erweitertescreening\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-652e096 e-con-full e-flex e-con e-child\" data-id=\"652e096\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t<div class=\"elementor-element elementor-element-565787e e-con-full e-flex e-con e-child\" data-id=\"565787e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-07dce84 elementor-widget elementor-widget-heading\" data-id=\"07dce84\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Extended screening in addition to the IRE test<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dd2cc7a elementor-widget elementor-widget-n-accordion\" data-id=\"dd2cc7a\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;multiple&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2310\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2310\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Killer Cell Receptor Typing (Blood Test) <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"hm hm-arrow-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"hm hm-arrow-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2310\" class=\"elementor-element elementor-element-5232211 e-con-full e-flex e-con e-child\" data-id=\"5232211\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-716be17 elementor-widget elementor-widget-text-editor\" data-id=\"716be17\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The uterine killer cells shield the semi-foreign embryo from the maternal immune system and produce important growth factors. There are activating or inhibiting receptors on the uterine killer cells, which significantly influence the killer cell function and the implantation process. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2311\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2311\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Autoimmune Screening (Blood Test) <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"hm hm-arrow-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"hm hm-arrow-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2311\" class=\"elementor-element elementor-element-85f60e6 e-con-full e-flex e-con e-child\" data-id=\"85f60e6\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2311\" class=\"elementor-element elementor-element-627ad92 e-flex e-con-boxed e-con e-child\" data-id=\"627ad92\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d414e66 elementor-widget elementor-widget-text-editor\" data-id=\"d414e66\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Autoantibodies against the body&#8217;s own tissue can be associated with an increased risk of miscarriage. An example of this is the so-called anti-phospholipid syndrome (APS), in which the immune system mistakenly forms antibodies against phospholipids, which can lead to an increased tendency to miscarriages. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2312\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2312\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Coagulation Diagnostics (Blood Test) <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"hm hm-arrow-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"hm hm-arrow-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2312\" class=\"elementor-element elementor-element-babf641 e-con-full e-flex e-con e-child\" data-id=\"babf641\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-46fc5a5 elementor-widget elementor-widget-text-editor\" data-id=\"46fc5a5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Another important component of the diagnostics is the exclusion of a tendency to thrombosis, which is a possible cause of placental dysfunction. A disturbed blood coagulation can impair the supply of the embryo and lead to miscarriages or growth disorders. Therefore, this possibility is checked by means of targeted blood tests.  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2313\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2313\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> HyCoSy (Ultrasound Contrast Agent Examination) <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"hm hm-arrow-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"hm hm-arrow-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2313\" class=\"elementor-element elementor-element-c58ffa7 e-con-full e-flex e-con e-child\" data-id=\"c58ffa7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2ac9615 elementor-widget elementor-widget-text-editor\" data-id=\"2ac9615\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>An ultrasound contrast agent examination (HyCoSy) is performed to visualize the uterus, ovaries and fallopian tubes and to check the patency of the fallopian tubes. This examination helps to rule out anatomical causes of implantation disorders, such as blocked fallopian tubes or structural abnormalities in the uterus that could impair the natural reproductive process. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2314\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2314\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Hysteroscopy (Outpatient Surgery with or without Anesthesia) <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"hm hm-arrow-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"hm hm-arrow-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2314\" class=\"elementor-element elementor-element-e2c5181 e-con-full e-flex e-con e-child\" data-id=\"e2c5181\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1e07d7a elementor-widget elementor-widget-text-editor\" data-id=\"1e07d7a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Hysteroscopy is an outpatient examination in which the uterus is viewed directly with the aid of a thin, flexible instrument, the hysteroscope. It can be performed with or without anesthesia and is used to clarify anatomical problems such as uterine malformations, myomas, polyps or adhesions, which can be possible causes of implantation disorders or repeated miscarriages. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2315\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"6\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2315\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Chromosome Analysis of both Partners (Blood Test) <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"hm hm-arrow-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"hm hm-arrow-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2315\" class=\"elementor-element elementor-element-73b1c11 e-con-full e-flex e-con e-child\" data-id=\"73b1c11\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ed83bf0 elementor-widget elementor-widget-text-editor\" data-id=\"ed83bf0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The chromosome analysis of both partners, a blood test, serves to exclude genetic abnormalities that could be inherited to the offspring. Certain genetic changes can increase the risk of miscarriage or lead to fertility problems. By analyzing the chromosomes of both partners, possible genetic causes for repeated miscarriages or unfulfilled desire to have children can be identified.  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-171c7e6a e-flex e-con-boxed e-con e-parent\" data-id=\"171c7e6a\" data-element_type=\"container\" data-e-type=\"container\" id=\"patienteninformationen\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9536b3 e-con-full e-flex e-con e-child\" data-id=\"9536b3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t<div class=\"elementor-element elementor-element-7e747a23 e-con-full e-flex e-con e-child\" data-id=\"7e747a23\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-57d65c59 uael-heading-align-left elementor-widget elementor-widget-uael-advanced-heading\" data-id=\"57d65c59\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"uael-advanced-heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"uael-module-content uael-heading-wrapper\">\n\t\t\t\t\t\t\t\t\t\t<div class=\"uael-sub-heading elementor-inline-editing\" data-elementor-setting-key=\"sub_heading\" data-elementor-inline-editing-toolbar=\"advanced\" >Downloads<\/div>\n\t\t\t\n\t\t\t<h2 class=\"uael-heading\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"uael-heading-text elementor-inline-editing uael-size--default\" data-elementor-setting-key=\"heading_title\" data-elementor-inline-editing-toolbar=\"basic\">Patient information<\/span>\n\t\t\t\t\t\t\t<\/h2>\n\n\t\t\t\n\t\t\t\t\t\t<div class=\"uael-module-content uael-separator-parent\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-separator\"><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-77e7ab4 uael-button-halign-left uael-tablet-button-halign-left uael-button-stack-tablet elementor-widget elementor-widget-uael-buttons\" data-id=\"77e7ab4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"uael-buttons.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"uael-dual-button-outer-wrap\">\n\t\t\t<div class=\"uael-dual-button-wrap\">\n\t\t\t\t\t\t\t\t<div class=\"uael-button-wrapper uael-dual-button elementor-widget-button elementor-repeater-item-4539a66 uael-dual-button-0\">\n\t\t\t\t\t<a class=\"elementor-button-link elementor-button elementor-size-sm elementor-button-link\" href=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/01\/flyer_implantationsdiagnostik.pdf\">\n\t\t\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper uael-buttons-icon-left\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-align-icon-left elementor-button-icon\">\n\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"huge huge-file-download\"><\/i>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text elementor-inline-editing\" data-elementor-setting-key=\"buttons.0.text\" data-elementor-inline-editing-toolbar=\"none\">Information flyer IRE Test<\/span>\n\t\t<\/span>\n\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"uael-button-wrapper uael-dual-button elementor-widget-button elementor-repeater-item-d610f9c uael-dual-button-1\">\n\t\t\t\t\t<a class=\"elementor-button-link elementor-button elementor-size-sm elementor-button-link\" href=\"https:\/\/www.green-ivf.de\/wp-content\/uploads\/2025\/01\/therapieplan_ire-test.pdf\">\n\t\t\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper uael-buttons-icon-left elementor-button-content-wrapper uael-buttons-icon-left\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-align-icon-left elementor-button-icon\">\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-calendar-alt\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M148 288h-40c-6.6 0-12-5.4-12-12v-40c0-6.6 5.4-12 12-12h40c6.6 0 12 5.4 12 12v40c0 6.6-5.4 12-12 12zm108-12v-40c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v40c0 6.6 5.4 12 12 12h40c6.6 0 12-5.4 12-12zm96 0v-40c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v40c0 6.6 5.4 12 12 12h40c6.6 0 12-5.4 12-12zm-96 96v-40c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v40c0 6.6 5.4 12 12 12h40c6.6 0 12-5.4 12-12zm-96 0v-40c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v40c0 6.6 5.4 12 12 12h40c6.6 0 12-5.4 12-12zm192 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